Casa 325 Key West

The Casa 325 Main Building

Two Person Studio Couch in Living Area Twin Bed Studio Two Person Studio One Bedroom Loft Four Person Studio
The Casa 325 Duval Street hotel in Old Town Key West Florida offers an ideal location right in the three hundred block of the main street where you’ll likely spend the majority of your vacation. Surrounded by shopping with all there is to see and do right outside your door. Mallory Square with its evening sunset celebration along with the best restaurants and bars are all within a short stroll from our property. We have a lovely pool and spacious suites that can accommodate up to four guests in a studio or two bedroom suite.

Our guesthouse is near the most popular section of Duval while being tucked away and providing privacy so you get the best of both worlds. There are many large hotels and resorts in the immediate area that charge exorbitant rates for their proximity to all the great attractions. We provide mini-fridges and microwaves in most rooms along with flat screen televisions. Whether you're looking for a spacious suite with multiple rooms or just a place to stay that's close to all the action without the high prices, come check us out.


A vacation to sunny southern Florida must include a visit to Key West and the preeminent focal point is Duval Street which has all the restaurants, bars and shops to keep a visitor busy for weeks on end and is close to the world renowned beaches that are Florida's claim to fame. Casa 325 is a quaint and surprisingly quiet hotel with all the amenities of home located directly on the main drag. Although it is right in the middle of all the action it remains a surprisingly quiet and affordable home away from home during your visit.

They're located on the other side of some buildings that provide a nice buffer against all the noise of a very happening bar town. That's the best description. You go in via this little walkway and it’s like stepping into another world. They are protected from noise, yet right on top of it. I was surprised how cheap it was. You are going to pay more to be in such a prime location. But the big name brand resorts neighboring this guesthouse are much higher in price. If you’re staying for more than a night and want to be able to literally walk to everything, you will not beat the casa 325.

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Off Season:
05/01 - 12/21: $145 - $295

12/21 - 05/01: $175 - $395

(Rates subject to change. Holidays and special events may be higher.)

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Casa 325 Map

    325 Duval Street
    Key West, Fl 33040

    Front Desk:




    • Poolside Location
    • Microwave
    • Fridge
    • Flat Screen TV
    • 2 Room Suites
    • Complimentary WiFi

Driving Distance

  • Fl City / Miles (Hours)

  • Middle Torch Key
    26 Mi (33 Min)
  • Tamiami
    152 Mi (3 Hrs 0 Min)
  • Oakland Park
    191 Mi (3 Hrs 42 Min)
  • Lake Worth
    222 Mi (4 Hrs 11 Min)
  • New Smyrna Beach
    404 Mi (7 Hrs 08 Min)
  • Palatka
    475 Mi (8 Hrs 15 Min)
  • Jasper
    563 Mi (9 Hrs 36 Min)
  • Havana
    Mi (11 Hrs 02 Min)
  • Graceville
    723 Mi (12 Hrs 15 Min)
  • Santa Rosa Beach
    776 Mi (13 Hrs 4 Min)
  • Pensacola
    831 Mi (13 Hrs 51 Min)